Sending to a List, with some exceptions

[Antonio Fernandez-Vicenti <afvaiv@xxxxxxxxxxxxxx>]

Hi, folks,
this is not specifically for PC, but rather general, for all types of 
e-mail.
Suppose you have a list of a certain number of people. Say, friends of 
yours.
Now you want to send them an e-mail, but you know some of your 
addressees specifically rejected to receive that type of message.
Can you specifically exclude them from the list for that specific e-mail?

What I mean is: some of my friends do reject any mail with any religious 
flavors... ; other, reject political or sex humour *.pps ; some other do 
not want receiving pictures, images (photos), etc
Having a different list for each type of content would be just too much 
for me.
I'd rather send whatever to the "List except  John, Joe, Pat" for 
example, since I know them all.

I'm just thinking of some type of "heading" like ".cc", ".cco", etc,  
but for the sake of "excluding some one from the List for this specific 
e-mail".
Can this be done in an easy way?
TIA