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You will need a new, fairly large server. For that number of
mailboxes, DO NOT run Exchange on the same system that is already
doing file & print, unless it is way under utilized and has lots of
free disk space. We also have a separate (small) proxy server outside
the firewall for OWA, so that the email server does not get hit
directly from the outside world.
We have a similar number of users; it takes ~1/2 a person to manage on
an ongoing basis.
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